Mental health and illness
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Using antipsychotics during breastfeeding
14 July 2025Quetiapine is the preferred second-generation, and haloperidol the preferred first-generation antipsychotic when breastfeeding full term, healthy infants.
Prescribing available medicines to treat ADHD
27 September 2023The availability of medicines used to treat Attention Deficit Hyperactivity Disorder (ADHD) varies currently. Supply content is maintained regularly by DHSC.
Using SSRI antidepressants during breastfeeding
13 January 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.
Deprescribing of antidepressants for depression and anxiety
4 December 2023Deprescribing antidepressants involves safely reducing and withdrawing them. An introduction; signposting to current resources; and SPS resources coming soon.
Using benzodiazepines during breastfeeding
15 February 2024Lorazepam and oxazepam are the preferred benzodiazepines during breast feeding, if clinically appropriate. Recommendations apply to full term, healthy infants.
Treating bipolar disorder during breastfeeding
5 October 2023Lithium and valproate can be used during breastfeeding, after consideration of some specific issues. Recommendations apply to full term and healthy infants.
Continuing management of the ADHD medicines shortage
16 November 2023Support for the system in continuing to manage supply disruption of medicines used to treat Attention Deficit Hyperactivity Disorder (ADHD).
Monitoring a person during and after antidepressant switching
17 February 2023Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.
Trazodone to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from trazodone to other antidepressants. Switches requiring additional specialist support are highlighted.
Establishing if a person needs to switch their antidepressant
17 February 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.