Mental health and illness
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Using tricyclic antidepressants during breastfeeding
17 November 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.
Switching strategies for antidepressants
22 May 2024The choice of antidepressant switching strategy depends on the person and antidepressant. We describe the current strategies and their application.
Supporting people with mental health conditions in primary care
19 September 2023Speakers shared experiences of supporting people living with mental health conditions to show that you don’t have to be an expert to make a contribution
Clozapine use in adults with swallowing difficulties
12 June 2023Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations
Treating bipolar disorder during breastfeeding
3 April 2024Lithium and valproate can be used during breastfeeding, after consideration of some specific issues. Recommendations apply to full term and healthy infants.
Using benzodiazepines during breastfeeding
15 February 2024Lorazepam and oxazepam are the preferred benzodiazepines during breast feeding, if clinically appropriate. Recommendations apply to full term, healthy infants.
Choosing an antidepressant for people with coronary heart disease
29 April 2025Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.
Trazodone to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely from trazodone to other antidepressants. Switches requiring additional specialist support are highlighted.
Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
Using SSRI antidepressants during breastfeeding
17 November 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.