Mental health and illness
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Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
Clozapine use in adults with swallowing difficulties
31 May 2023Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations
Supporting people with mental health conditions in primary care
19 September 2023Speakers shared experiences of supporting people living with mental health conditions to show that you don’t have to be an expert to make a contribution
Choosing an antidepressant for people with coronary heart disease
29 April 2025Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.
Treating opioid dependence during breastfeeding
1 August 2023Methadone is the preferred choice of treatment for opioid dependence during breastfeeding. Recommendations apply to full term and healthy infants only.
Using certain antidepressants during breastfeeding
15 November 2023Duloxetine, mirtazapine, trazodone or venlafaxine can be used with caution but other options are preferred. Recommendations apply to full term, healthy infants.
Mental health medicines: resources to support answering questions
3 February 2023Suggested resources to help primary care healthcare professionals find information on psychotropic and other medicines used in psychiatry
Using antidepressants for depression in people with epilepsy
14 May 2021Antidepressant use requires special consideration in people with epilepsy. Treating depression in stable epilepsy is covered.
SSRIs to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
Vortioxetine to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from vortioxetine to other antidepressants. Switches requiring additional specialist support are highlighted.