Mental health and illness
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Establishing if a person needs to switch their antidepressant
28 March 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.
Monitoring a person during and after antidepressant switching
17 September 2024Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.
Addressing inappropriate use of antidepressants for depression and anxiety
20 January 2026Deprescribing antidepressants involves safely reducing and withdrawing them. An introduction; signposting to current resources; and SPS resources coming soon.
Continuing management of the ADHD medicines shortage
15 July 2024Support for the system in continuing to manage supply disruption of medicines used to treat Attention Deficit Hyperactivity Disorder (ADHD).
Mental health medicines: resources to support answering questions
9 January 2024Suggested resources to help primary care healthcare professionals find information on psychotropic and other medicines used in psychiatry
MAOI to other antidepressants: switching in adults
31 May 2024Switching between or from a monoamine oxidase inhibitor (MAOI) is a complex switch and requires support from a specialist. General principles are described.
Agomelatine to other antidepressants: switching in adults
17 September 2024Suggested methods for switching safely from agomelatine to other antidepressants. Switches requiring additional specialist support are highlighted.
SSRIs to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
Vortioxetine to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely from vortioxetine to other antidepressants. Switches requiring additional specialist support are highlighted.
Prescribing and switching between modified-release methylphenidate
28 August 2025Modified-release methylphenidate capsules and tablets differ. Ensure patients receive appropriate treatment, particularly during periods of supply disruption.