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Establishing if a person needs to switch their antidepressant

17 February 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.

Monitoring a person during and after antidepressant switching

17 February 2023Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of discontinuation and serotonin syndromes.

Planning and agreeing an antidepressant switching strategy

17 February 2023Guidance on planning and implementing the antidepressant switch after the need and choice of antidepressant have been decided.

Tricyclics to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely between tricyclics or to other antidepressants. Switches requiring additional specialist support are highlighted.

SSRIs to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.

Using tricyclic antidepressants during breastfeeding

31 January 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.

Using SSRI antidepressants during breastfeeding

13 January 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.

Managing constipation in people taking clozapine

14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.

Depression: treatment during pregnancy

6 January 2022Signposting evidence-based information on the treatment of depression in pregnancy

Choosing an antidepressant for people with coronary heart disease

2 July 2021Making a suitable choice of antidepressant in CHD needs to include considerations of both the patient and the characteristics of the medicines.

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NHS