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Anaesthesia and pain
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Clonidine products: information for supporting intrathecal risk assessment
11 August 2022
·
Clonidine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration
Using opioids for pain relief during pregnancy
10 August 2022
·
Opioid analgesics may be used at any stage of pregnancy at the lowest effective dose for the short-term relief of pain when other analgesics are not effective
Pain: treatment during pregnancy
6 January 2022
·
Signposting evidence-based information on the treatment of pain in pregnancy
Switching between oral morphine and other oral opioids in adult palliative cancer care patients
14 September 2021
·
Switching between morphine and alternative opioids requires care and thoughtful application of a stepped process
Safety in Lactation: Antimuscarinic drugs
5 November 2020
·
These antimuscarinics are used as premedication, to dry secretions, and for intraoperative bradycardia. They are given as a single dose by injection, repeated if necessary…
Safety in Lactation: Antimigraine drugs
21 October 2020
·
If simple analgesics, e.g. paracetamol and ibuprofen, are insufficient to treat symptoms, sumatriptan is the drug of choice for the treatment of acute migraine. Although…
Safety in Lactation: Opioid analgesics
21 October 2020
·
The evidence relating to the safe use of opioid analgesics in breastfeeding mothers is very variable between individual drugs. This group of drugs presents a…
Safety in Lactation: Local anaesthetic eye preparations
15 October 2020
·
Local anaesthetics for ophthalmic use have limited systemic absorption in the mother, and pose negligible risk to a breastfed infant. Systemic absorption from eye drops…
Safety in Lactation: Sedative and analgesic peri-operative drugs
25 September 2020
·
Benzodiazepines are used for premedication and for conscious sedation during surgery. Following short–term therapy (1-2 doses) for these indications, it is considered that breastfeeding can…
Safety in Lactation: Local anaesthesia
25 September 2020
·
Local anaesthetics are generally considered to be compatible with breastfeeding. They are used in a variety of clinical situations (surgery including Caesarean sections, labour and…
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