Anaesthesia and pain

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Anaesthesia and pain

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Levobupivacaine products: information for supporting intrathecal risk assessment

11 August 2022Levobupivacaine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Ziconotide products: information for supporting intrathecal risk assessment

11 August 2022Ziconotide products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Clonidine products: information for supporting intrathecal risk assessment

11 August 2022Clonidine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Using opioids for pain relief during pregnancy

10 August 2022Opioid analgesics may be used at any stage of pregnancy at the lowest effective dose for the short-term relief of pain when other analgesics are not effective.

Pain: treatment during pregnancy

6 January 2022Signposting evidence-based information on the treatment of pain in pregnancy

Switching between oral morphine and other oral opioids in adult palliative cancer care patients

14 September 2021Switching between morphine and alternative opioids requires care and thoughtful application of a stepped process

Safety in Lactation: Antimigraine drugs

21 October 2020If simple analgesics, e.g. paracetamol and ibuprofen, are insufficient to treat symptoms, sumatriptan is the drug of choice for the treatment of acute migraine. Although…

Safety in Lactation: Local anaesthetic eye preparations

15 October 2020Local anaesthetics for ophthalmic use have limited systemic absorption in the mother, and pose negligible risk to a breastfed infant. Systemic absorption from eye drops…

Safety in Lactation: Sedative and analgesic peri-operative drugs

25 September 2020Benzodiazepines are used for premedication and for conscious sedation during surgery. Following short–term therapy (1-2 doses) for these indications, it is considered that breastfeeding can…

Safety in Lactation: Local anaesthesia

25 September 2020Local anaesthetics are generally considered to be compatible with breastfeeding. They are used in a variety of clinical situations (surgery including Caesarean sections, labour and…

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