Mental health and illness
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Using tricyclic antidepressants during breastfeeding
31 January 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.
Switching strategies for antidepressants
22 May 2024The choice of antidepressant switching strategy depends on the person and antidepressant. We describe the current strategies and their application.
SNRIs to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely between SNRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
Tricyclics to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely between tricyclics or to other antidepressants. Switches requiring additional specialist support are highlighted.
Considerations when choosing an alternative antidepressant
17 February 2023Consider the risks associated with switching an antidepressant for depression, the patient's individual circumstances and when to seek specialist advice.
Mirtazapine to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from mirtazapine to other antidepressants. Switches requiring additional specialist support are highlighted.
Moclobemide to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from moclobemide to other antidepressants. Switches requiring additional specialist support are highlighted.
Supporting system response to the ADHD medicine shortage
16 November 2023Practical advice for the system in response to the NatPSA for Attention Deficit Hyperactivity Disorder (ADHD) medicines.
SSRI suggestions for adults with swallowing difficulties
20 June 2024A range of selective serotonin reuptake inhibitor (SSRI) formulations are suitable for adults with swallowing difficulties.
Oral benzodiazepines and choosing equivalent doses
2 July 2025Equivalent doses of oral benzodiazepines to diazepam are not exact. Consider these factors before switching.