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Safety in Pregnancy

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The risks and principles of prescribing in pregnancy

15 July 2025Prescribing in pregnancy requires balancing maternal and fetal risks. This guidance outlines key risks and principles to ensure safe, informed decisions.

Information resources for advice about medicines in pregnancy

15 July 2025SPS and other resources can help pharmacy and other healthcare professionals provide advice on medicines in pregnancy.

Conducting a medicines risk assessment in pregnancy

15 July 2025The questions asked should provide information on factors that are critical to the risk assessment for each individual pregnancy.

Pain: treatment during pregnancy

3 April 2025A summary of pharmacological options commonly used to treat pain in primary care.

Vitamin D deficiency: treatment during pregnancy

5 March 2025Use oral vitamin D therapy to manage vitamin D deficiency during pregnancy. It is important to prescribe an appropriate formulation and dose.

Haemorrhoids: treatment during pregnancy

4 March 2025Use non-pharmacological treatment for the management of haemorrhoids during pregnancy. If insufficient use a topical haemorrhoidal preparation.

Hay fever or allergic rhinitis: treatment during pregnancy

31 January 2025Use non-pharmacological treatments for the initial management of hay fever during pregnancy. If insufficient, use topical treatments or oral antihistamines.

Vitamin B12 deficiency: treatment during pregnancy

27 November 2024Intramuscular hydroxocobalamin and oral cyanocobalamin are treatment options for the management of clinically relevant vitamin B12 deficiency during pregnancy.

Omeprazole for use within antenatal and maternity services

20 April 2023SPS protocol templates for the supply and administration of omeprazole for pre planned caesarean section by registered midwives.

Terbutaline injection for use in labour within maternity services

19 January 2023SPS PGD template for administering subcutaneous terbutaline sulfate for the reduction of contraction frequency in individuals in labour.