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Depression and anxiety

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Mirtazapine to other antidepressants: switching in adults

31 May 2024Suggested methods for switching safely from mirtazapine to other antidepressants. Switches requiring additional specialist support are highlighted.

Trazodone to other antidepressants: switching in adults

31 May 2024Suggested methods for switching safely from trazodone to other antidepressants. Switches requiring additional specialist support are highlighted.

MAOI to other antidepressants: switching in adults

31 May 2024Switching between or from a monoamine oxidase inhibitor (MAOI) is a complex switch and requires support from a specialist. General principles are described.

Vortioxetine to other antidepressants: switching in adults

31 May 2024Suggested methods for switching safely from vortioxetine to other antidepressants. Switches requiring additional specialist support are highlighted.

SSRIs to other antidepressants: switching in adults

31 May 2024Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.

Switching strategies for antidepressants

22 May 2024The choice of antidepressant switching strategy depends on the person and antidepressant. We describe the current strategies and their application.

Using antidepressants for depression in people with epilepsy

21 February 2024Antidepressant use requires special consideration in people with epilepsy. Treating depression in stable epilepsy is covered.

Using tricyclic antidepressants during breastfeeding

17 November 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.

Using SSRI antidepressants during breastfeeding

17 November 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.

Using certain antidepressants during breastfeeding

17 November 2023Duloxetine, mirtazapine, trazodone or venlafaxine can be used with caution but other options are preferred. Recommendations apply to full term, healthy infants.