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Suggestions for Therapeutic Drug Monitoring in Adults in Primary Care

29 September 2020This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care.    The monitoring parameters cited…

Safety in lactation: Drugs for chronic bowel disorders

21 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Aminosalicylates for chronic bowel disorders Mesalazine…

Safety in Lactation: Systemic preparations for eczema and psoriasis

7 January 2019Drugs used orally or parenterally for severe eczema and psoriasis have a varied pharmacology, mainly either modifying the immune response to the disease or modifying…
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Medicine Compliance Aid Stability

ImuranAspen

Aspen
Imuran
Tablets f/c 25mg, 50mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from light. Airtight container
25 September 2015

Lactation Safety Information

In transplantation

In transplantation
See summary
Moderate level of published evidence of use in breastfeeding
Small amounts of active metabolite, 6-mercaptopurine, in breast milk
If high dose used, monitor infant blood counts
24 September 2020

For rheumatoid arthritis

For rheumatoid arthritis
See summary
Moderate level of published evidence of use in breastfeeding
Small amounts of active metabolite, 6-mercaptopurine, in breast milk
If high dose used, monitor infant blood counts
24 September 2020

For eczema

For eczema
Topical eczema preparation / corticosteroid if appropriate
Unlicensed indication in the UK
Moderate level of published evidence of use in breastfeeding
Small amounts of active metabolite, 6-mercaptopurine, in breast milk
Monitor for signs of infection and immunosuppression, and, if high dose used, infant blood counts
24 September 2020

For inflammatory bowel disease

For inflammatory bowel disease
See summary
Moderate level of published evidence of use in breastfeeding
Small amounts of active metabolite, 6-mercaptopurine, in breast milk
If high dose used, monitor infant blood counts
24 September 2020