Licensed for intrathecal use
Products licensed for intrathecal use are the first line option and should be used wherever suitable.
Accord
Strength
20 mg/mL in 2mL vial
20 mg/mL in 5mL vial
Hospira
Strength
20 mg/mL in 5mL vial
20 mg/mL in 25mL vial
20 mg/mL in 50mL vial
Not licensed for intrathecal use, limited information available
Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Inclusion of a product on this page does not constitute a recommendation for intrathecal use. The information is provided to help healthcare providers in local decision-making only. Refer to the advice in our article (SPS page) and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.
Accord
Strength
100 mg/mL in 1mL vial
100 mg/mL in 5mL vial
100 mg/mL in 10mL vial
100 mg/mL in 20mL vial
100 mg/mL in 40mL vial
100 mg/mL in 50mL vial
Excipients
Macrogol 400, trometamol (for pH adjustment), water for injection
Osmolarity / osmolality
No information
pH
7.0 – 9.5
Endotoxin content
≤0.07 EU/mg
Hospira
Strength
100 mg/mL in 1mL vial
100 mg/mL in 5mL vial
100 mg/mL in 10mL vial
100 mg/mL in 20mL vial
Excipients
Water for injection, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment)
Osmolarity / osmolality
287 – 336 mOsm/kg
pH
8.61 – 8.77
Endotoxin content
No information
No information available
Products with very little or no information are rarely used for intrathecal administration.
There are currently no known additional cytarabine products.
Update history
- Addition made to unlicensed advice wording
- Republished
- Full update to monograph
- Title and URL shortened.
- Updated links
- Published