Licensed for intrathecal use
Products licensed for intrathecal use are the first line option and should be used wherever suitable.
There are currently no known etoposide products licensed for intrathecal administration.
Not licensed for intrathecal use, limited information available
Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Refer to the advice in our article and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.
Accord
Strength
20mg/mL in 5mL vial
20mg/mL in 10mL vial
20mg/mL in 12.5mL vial
20mg/mL in 20mL vial
20mg/ml in 25mL vial
20mg/mL in 50mL vial
Excipients
Citric acid, anhydrous, benzyl alcohol (30 mg/ml), polysorbate 80, macrogol 300, ethanol, anhydrous (240.64 mg/ml)
Osmolarity / osmolality
No information
pH
3.0 – 4.0
Endotoxin content
≤ 1.3 EU/mg
Hikma
Strength
20mg/mL in 5mL ampoule
20mg/mL in 10mL ampoule
20mg/mL in 20mL ampoule
20mg/ml in 25mL ampoule
20mg/mL in 50mL ampoule
Excipients
Citric acid anhydrous, benzyl alcohol, polysorbate 80, polyethyleneglycol , ethanol 96%
Osmolarity / osmolality
338 – 404 mOsm/kg
pH
3.1 – 4.0
Endotoxin content
≤ 5 IU/mL
Fresenius
Strength
20mg/mL in 5mL vial
20mg/mL in 10mL vial
20mg/mL in 25mL vial
20mg/mL in 50mL vial
Excipients
Macrogol 300, polysorbate 80, benzyl alcohol (30mg/mL), ethanol (241.4 mg/mL), citric acid (anhydrous)
Osmolarity / osmolality
No information
pH
3 – 4
Endotoxin content
≤ 2.0 EU/mg
Neon (Etopophos®)
Strength
Excipients
Dextran 40, Sodium citrate
Osmolarity / osmolality
No information
pH
No information
Endotoxin content
No information
Update history
- Republished
- Full monograph update
- Title and URL shortened.
- Published