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Interactions

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Guidance
Interactions

Drug interactions: resources to support answering questions

20 March 2023 · Suggested resources to help primary care healthcare professionals find information to answer questions about drug interactions

Guidance

Interactions

All our advice relating to medicine interactions, with recommendations on management options.

Related

Considerations and interactions with GLP-1 receptor agonists

Signposting key risks and interactions of GLP-1 receptor agonists in diabetes, obesity, and weight management.

Tirzepatide · 24 October 2025

Managing interactions between medicines and enteral feeds

Learn about the types of feed, some of the most common medicine and feed interactions and how to manage them.

Warfarin · 18 September 2025

Considering interactions with local anaesthetics in dentistry

Interpreting significance of drug interactions with dental local anaesthetic (LA) cartridges and why most aren’t clinically relevant in general dental practice.

Prilocaine + Felypressin · 3 January 2025

Managing interactions with local anaesthetics in dentistry

Most drug interactions with local anaesthetics (LA) cartridges are not clinically relevant in general dentistry. We advise on management options where needed.

Vernakalant · 3 January 2025

Understanding enzyme or transporter-based drug interactions

Many interactions are due to inhibition or induction of metabolising enzymes or drug transporters. Enzyme, transporter, and drug half-lives dictate duration.

Interactions · 22 May 2024

Using folic acid and phenytoin safely

Folic acid interacts with phenytoin and can reduce phenytoin blood levels. Concomitant use is possible with careful management of the interaction.

Phenytoin · 12 April 2024

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