Variation in practice underlined the need for an evidence-based guideline for handling mAbs that was suited to all those providing care to NHS patients.

This guideline does not provide prescriptive recommendations for the preparation and handling of each specific mAb in every healthcare organisation due to the many influencing clinical and operational factors unique to operations in each organisation. Rather, the guideline provides a mechanism and guidance for individual organisations to assess these factors in their own facilities and suggests a range of suitable risk minimisation and control measures that may need to be considered.


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