Small amounts in breast milk

Moderate published evidence of use in breastfeeding

Minimal absorption from the infant’s GI tract

Used in full-term neonates from birth

Limited published evidence of safety

This entry applies to all uses (infiltration, regional and surface anaesthesia and nerve blocks) and formulations (injection/topical) of lidocaine for local anaesthesia, including injections with adrenaline

Small amounts in breast milk and minimal absorption from the infant’s GI tract

Only available in combination with fluorescein for which there are no additional risks

Topical/rectal use for short periods in combination with a corticosteroid considered to present minimal risk to breastfed infant

Sep 20 · No plans to launch in the UK anytime soon [4].

Jul 20 · Lidocaine (Lidbree) 42 mg/mL intrauterine gel was approved in the UK for topical anaesthesia for moderate acute pain during cervical and intrauterine procedures, in adults and adolescents from 15 years of age [1].

Some women feel no or only mild pain during a hysteroscopy, but for others the pain can be severe [2]. Cervical biopsy and cervical curettage are associated with visual analogue scale (VAS) pain scores ranging from four to six on a 10-point scale. Endometrial biopsies done have VAS scores of five to seven. Pain with intrauterine device insertion varies from two to seven, and pain scores during laminaria insertions with paracervical block range from five to seven [3].

SPC