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Medroxyprogesterone acetate (SC-DMPA) injection for contraception

5 October 2021SPS PGD template for the supply and/or administration of subcutaneous medroxyprogesterone acetate (SC-DMPA) injection for contraception.

Medroxyprogesterone acetate (DMPA) IM injection for contraception

5 October 2021SPS PGD template for administering intramuscular (IM) medroxyprogesterone acetate (DMPA) injection for contraception.

What injections can be given orally or via enteral feeding tubes?

6 November 2020This updated Medicines Q&A is a quick reference summary to different types of enteral feeding tubes, in relation to medication issues. Not all enteral feeding…

Safety in Lactation: Progestogen-only contraceptives

30 October 2020Progesterone-only contraceptives (POC) are administered orally, by depot injection, intradermal implant or intra-uterine device. There is no evidence that POCs have any effects on breastfeeding…
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Lactation Safety Information

Oral

Oral
No published evidence of use in breastfeeding when used as oral therapy. However, evidence for the injection shows it passes into breast milk in very small amounts.
Very low oral bioavailability of medroxyprogesterone means the infant is unlikely to absorb significant amounts from breast milk.
No side-effects have been reported in infants exposed to medroxyprogesterone via breast milk.
If high doses are required, for example doses above 200mg for use in cancer, contact UKDILAS for further advice.
As a precaution, monitor the infant for changes in feeding.
18 April 2023

Injection as a contraceptive

Injection as a contraceptive
Nonhormonal contraception
Moderate level of published evidence which shows it passes into breast milk in very small amounts.
Very low oral bioavailability of medroxyprogesterone means the infant is unlikely to absorb significant amounts from breast milk.
No side-effects have been reported in infants exposed to medroxyprogesterone via breast milk.
As a precaution, monitor the infant for changes in feeding.
3 April 2023