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Safety in Lactation: Antidepressants

21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…

What is serotonin syndrome and which medicines cause it?

22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.  

What evidence is available for the use of antidepressants for the management of menopausal hot flushes?

26 November 2019This is one of two UKMi Medicines Q&As addressing the management of menopausal hot flushes (vasomotor symptoms) with non-hormonal drug therapy.

How do you switch between monoamine oxidase inhibitors and SSRI, tricyclic or related antidepressants?

9 September 2019This updated Medicines Q&A provides advice on the risks and suggested strategies for switching between monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRI),…
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Medicine Compliance Aid Stability

ManerixMeda

Meda
Manerix
Tablets 150mg, 300mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage.
3 January 2013

genericSandoz Ltd

Sandoz Ltd
generic
Tablets 150mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage.
1 March 2013

Lactation Safety Information

TCA: imipramine/nortriptyline SSRI: paroxetine/sertraline
Limited published evidence of safety
Small amounts in breast milk
Monitor infant for drowsiness, poor feeding and restlessness
5 June 2018