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Diamorphine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Licensed for intrathecal use

Products licensed for intrathecal use are the first line option and should be used wherever suitable.

There are currently no known diamorphine products licensed for intrathecal administration.

Not licensed for intrathecal use, limited information available

Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Refer to the advice in our article and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.

Wockhardt

Strength

5 mg ampoule

10 mg ampoule

30 mg ampoule

100 mg ampoule

500 mg ampoule

Excipients

Water for injection (not detectable in the finished product)

Osmolarity / osmolality

Information not available

pH

Information not available

Endotoxin content

≤5.0 IU/mg

Unlicensed ‘Special’, specified for intrathecal use

Unlicensed medicines that are manufactured in MHRA-licensed Specials Manufacturing Units, at the request of an authorised healthcare professional specifically for intrathecal use.

Preston Pharmaceuticals – Royal Preston Hospital

Strength

500 micrograms in 0.5mL PFS

Queen Alexandra Hospital, Portsmouth

Strength

1mg/mL in 1mL PFS

Royal Hospitals, Belfast – Victoria Pharmaceuticals

Strength

500 micrograms/mL in 1mL PFS

Royal Liverpool Hospitals Foundation Trust

Strength

300 micrograms in 0.3mL PFS
500 micrograms in 0.5mL PFS

Stepping Hill Hospital – Stockport Pharmaceuticals

Strength

1mg/mL in 1mL PFS

 

Update history

  1. Republished
  2. Full monograph update
  1. Title and URL shortened.
  1. Published