Signposting evidence-based information on the treatment of diabetes in pregnancy

Condition management

It is important to complete an individual risk assessment for your patient and to apply the principles of prescribing during pregnancy when looking at the available information and making treatment decisions. Check to see if a risk assessment has already been completed by the specialist team.

Untreated or inadequately treated diabetes can have adverse effects on the mother and therefore on the foetus.

NICE guideline [NG3] Diabetes in pregnancy: management from preconception to the postnatal period provides comprehensive guidance on overall condition management. This guideline includes recommendations on:

You should check if there is local guidance for you to use in your area.

Pregnancy outcome information

UK Teratology Information Service (UKTIS) provides overviews on diabetes and the use of insulin and on the use of antidiabetics in pregnancy.

More detailed information on pregnancy outcomes for specific medicines including metformin and glibenclamide is also available.

Patient information

Each of the UKTIS summaries has corresponding Best Use of Medicine in Pregnancy (BUMPS) patient information.

The Royal College of Obstetricians and Gynaecologists (RCOG) provide information about gestational diabetes.

NHS Medicines A-Z provides information on diabetes and pregnancy and also a summary statement on the use in pregnancy of specific antidiabetic medicines.

The pregnancy information provides patient information on conditions in pregnancy including diabetes and pregnancy

The Medicines A-Z has a summary statement on the use in pregnancy of the common antidiabetic medicines.


Support for prescribing decisions in people on interacting medicines, those with swallowing difficulties, renal impairment, or who are pregnant or breastfeeding
SPS protocol templates for the supply and administration of omeprazole for pre planned caesarean section by registered midwives.
SPS PGD template for administering subcutaneous terbutaline sulfate for the reduction of contraction frequency in individuals in labour.
SPS PGD template for the intrapartum administration of benzylpenicillin for prevention of early-onset Group B Streptococcus (GBS) infection in neonates.
Opioid analgesics may be used at any stage of pregnancy at the lowest effective dose for the short-term relief of pain when other analgesics are not effective.
Intramuscular hydroxocobalamin is the preferred treatment choice for management of clinically relevant vitamin B12 deficiency, including during pregnancy.
SPS PGD template for the supply of folic acid 5mg tablets to reduce risk of neural tube defect or compensate for increased folate demand during pregnancy.
SPS PGD template for the supply of aspirin tablets to individuals at risk of pre-eclampsia during pregnancy.
Signposting evidence-based information on the treatment of pain in pregnancy
Signposting evidence-based information on the treatment of urinary tract infection in pregnancy

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