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Using strong opioid analgesics during breastfeeding

26 May 2023Morphine is the strong opioid analgesic of choice for treating pain in breastfeeding. Recommendations apply to full term and healthy infants only.

Morphine products: information for supporting intrathecal risk assessment

11 August 2022Morphine sulfate products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Using opioids for pain relief during pregnancy

10 August 2022Opioid analgesics may be used at any stage of pregnancy at the lowest effective dose for the short-term relief of pain when other analgesics are not effective.

Example medicines to prescribe by brand name in primary care

27 March 2022Prescribe certain medicines by brand to ensure supply of the same product. Examples are grouped by therapeutic area. The list of products is not exhaustive.

Supply and/or administration of Controlled Drugs under a PGD

16 November 2021The legal position on the supply and/or administration of controlled drugs under Patient Group Directions is summarised
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Lactation Safety Information

Except for low dose, immediate release oral formulations

Except for low dose, immediate release oral formulations
Other appropriate analgesic
Significant published evidence of use in breastfeeding
Small amounts in breast milk
Used in full-term neonates from birth
Infant monitoring advised, especially in young infants (see summary)
23 September 2020

Low dose, immediate release oral formulations

Low dose, immediate release oral formulations
Yes
Significant published evidence of use in breastfeeding
Small amounts in breast milk
Applies to short term, low dose (up to 10mg 4-hourly) oral solutions (e.g. Oramorph) and tablets
Although adverse effects in infant are not likely infant monitoring advised in young infants (see summary)
23 September 2020